The response of the Indian Summer Monsoon (ISM) to forcing factors and climate variables has not yet fully explored, even though the ISM plays a pivotal role in the socio-economics of the Indian subcontinent and nearby areas. The ISM progression over Indian landmass is a manifestation of the Intertropical Convergence Zone (ITCZ) migration over the northern Indian Ocean and the Indian subcontinent. The recent anomalous behaviour of ISM raises the need for a better understanding of its spatio-temporal changes during the ongoing interglacial period termed as the Holocene period. The Holocene period has been classified further based on the globally observed abrupt climatic events at 8.2 and 4.2 ka. The 8.2 ka global cooling events have been recorded from northern Indian Ocean marine archives but limited records from the continental archives of the Indian landmass has demonstrated the 8.2 ka event. At the same time, the 4.2 ka dry climate has been endorsed by both marine as well as continental records and agrees with the global studies. During the ‘Little Ice Age’ (LIA), in the India subcontinent, wet conditions prevailed in the northern, central and western regions while a dry climate existed over the greater part of peninsular India. The present review offers an account of ISM signatures and possible mechanisms associated with the monsoon variability in the Indian subcontinent and the northern Indian Ocean during the Holocene period.