There has been an age old assertion that once public policies are formulated, the policies will automatically be implemented to achieve their stated objectives. To unravel this, the article through comparative empirical analysis discussed the dynamics that influenced local economic development implementation in Ghana. It emerged that four key dynamics: politics, leadership commitment and will, land tenure system and administrative, institutional and procedural mechanisms differently shaped local economic development implementation in the three local government units. Whereas these factors promoted local economic development implementation in some of the assemblies, it hindered its successful implementation in others. The findings of this article are of significance to local economic development and local governance practitioners and politicians as they strife to implement local economic development policies.